Why did the cytoplasm fraction produce lactic acid in the presence of both glucose and pyruvate?
Show Understanding: • In glycolysis, glucose is converted into pyruvate in the cytoplasm
At the end of glycolysis, the following reactions have occurred:
Overview of Glycolysis Understanding: • Glycolysis gives a small net gain of ATP without the use of oxygen
Aerobic Respiration
Anaerobic Respiration (Fermentation)
Anaerobic Respiration (Fermentation) Why did the mitochondria produce carbon dioxide in the presence of pyruvate?Why would the mitochondria produce carbon dioxide in the presence of pyruvate but not in the presence of glucose? Mitochondria cannot use glucose. It uses pyruvate to go through the link reaction and Krebs cycle were CO2 is produced.
Why do cells convert pyruvate to lactic acid?In the absence of oxygen (anaerobic), pyruvate must be converted to lactic acid, the only reaction that can regenerate NAD+ allowing further glycolysis.
Why does pyruvate need to be converted to lactic acid in order for glycolysis to continue in the absence of oxygen?Since glycolysis doesn't rely on oxygen, this is the only pathway to provide a stable energy source during oxygen deprivation. So in order to regenerate the needed for glycolysis to continue, it needs to donate its electrons onto pyruvate, which produces lactic acid.
Why is pyruvate converted to lactate in anaerobic conditions?If a cell lacks mitochondria, is poorly oxygenated, or energy demand has rapidly increased to exceed the rate at which oxidative phosphorylation can provide sufficient ATP, pyruvate can be converted to lactate by the enzyme lactate dehydrogenase.
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