Which drug is directly myelosuppressive and may induce thrombocytopenia Quizlet
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clots form in small vessels (can be med emergency), may be due to certain drugs (e.g., Plavix, chemo) or pregnancy, lupus, scleroderma; Show bleeding and clotting SIMULTANEOUSLY; enhanced aggregation of platelets causes micro-thrombi to form and deposit in vessels Uncommon syndrome characterized by
hemolytic anemia, thrombocytopenia, neurologic abnormalities, fever, and renal abnormalities. Treat underlying disorder first (e.g. infection) or remove causative agent; can treat: Proliferation of immature white blood cells Replacement of bone marrow with blast cells Reduction in RBC, WBC, and platelet count Occurrence of anemia, pallor, and infection In leukemia, immature white blood cells such as malignant and blast cells proliferate. Blast cells replace bone marrow resulting in bone marrow failure, which causes a decrease in RBC, WBC, and platelet count. Anemia and pallor occur due to reduction in RBC count. The decrease in WBC count leads to immunosuppression resulting in infection. Recommended textbook solutions
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Which drugs can induce thrombocytopenia?Heparin, a blood thinner, is the most common cause of drug-induced immune thrombocytopenia.. Furosemide.. Gold, used to treat arthritis.. Nonsteroidal anti-inflammatory drugs (NSAIDs). Penicillin.. Quinidine.. Quinine.. Ranitidine.. Sulfonamides.. Which drug is directly Myelosuppressive?Some common chemotherapy drugs that may cause myelosuppression are: Fluorouracil: This drug can cause all forms of myelosuppression. Oxaliplatin: This medication can cause neutropenia and thrombocytopenia. Irinotecan: This agent can lead to neutropenia.
Which drug would be the most common cause of drugHeparin-induced thrombocytopenia (HIT) is technically the most common cause of drug-associated thrombocytopenia, but the drop in platelet levels in patients with HIT is rarely sufficient to provoke bleeding and thrombosis is the major clinical complication.
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