What is the probability of a homozygous dominant offspring for these two parents?

Dominant Inheritance

When a trait is dominant, only one allele is required for the trait to be observed. A dominant allele will mask a recessive allele, if present. A dominant allele is denoted by a capital letter (A versus a). Since each parent provides one allele, the possible combinations are: AA, Aa, and aa. Offspring whose genotype is either AA or Aa will have the dominant trait expressed phenotypically, while aa individuals express the recessive trait.

One example of a dominantly inherited trait is the presence of a widow’s peak (a V-shape) at the hairline.

What is the probability of a homozygous dominant offspring for these two parents?
Let (W) represent the dominant allele, and (w) represent the recessive allele.  An individual with a (WW) or (Ww) genotype will have a V-shaped peak at the hairline. Only ww individuals will have a straight hairline. To determine the probability of inheritance of a widow’s peak (or any other dominant trait), the genotypes of the parents must be considered. For
What is the probability of a homozygous dominant offspring for these two parents?
example, if one parent is homozygous dominant (WW) and the other is homozygous recessive (ww), then all their offspring will be heterozygous (Ww) and possess a widow’s peak. If both parents are heterozygous (Ww), there is a 75% chance that any one of their offspring will have a widow’s peak (see figure). A Punnett square can be used to determine all possible genotypic combinations in the parents.

Pedigree

A pedigree that depicts a dominantly inherited trait has a few key distinctions. Every affected individual must have an affected parent. Dominantly inherited traits do not skip generations. Lastly, males and females are equally likely to receive a dominant allele and express the trait. In this pedigree both heterozygous and homozygous individuals are affected since the trait is dominant.

What is the probability of a homozygous dominant offspring for these two parents?
Image courtesy of Michael A. Kahn, DDS

CLICK HERE to learn more about patterns of inheritance
CLICK HERE to learn more about recessive inheritance
CLICK HERE to learn more about X-linked inheritance

Here, we will study a table named Punnett square. This table is useful in calculating the probabilities of offspring with certain genetic characteristics.

Introduction:

Probability and statistics are closely related and have important applications in science. In the same way, probability and genetics are also very closely related! Incidences of genetically inherited traits are just instances of probability.

Common Terminology

Alleles: A person's characteristics are the consequence of how the genetic material is paired. This genetic material is known as alleles. It is the framework of these alleles that determines the traits of an individual, like hair color, eye color, height, etc. Certain alleles are dominant, and certain are regressive. A person with one or two dominant alleles exhibits the dominant trait. And a person who has two recessive alleles displays the recessive characteristic.

Genotype: The specific pairing of alleles that an individual inherits that code for a specific trait, is known as a genotype.

Phenotype: The actual physical trait or appearance is known as the phenotype - meaning regardless of the actual genotype, the phenotype is the resulting characteristic of that genotype.

Confusing, right? Let’s look at an example. What determines the hair color of an individual?

  • There's a dominant allele ‘B’ that represents black hair color, and there's a recessive allele ‘b’ that represents brown hair color.
  • Persons whose alleles are paired as BB or Bb both have black hair. The person has black hair even if the pairing of alleles is different!
  • In this case, the particular pair of alleles is known as the person's genotype (the collection of genes an individual has imbibed). In order for an individual to have brown hair, they’d need to have a bb genotype. Black hair would be the phenotype and Bb or BB would be the genotype.
  • So if you think about it, there are two genotypes for the phenotype of black hair. However, only people who have bb pairing will have brown hair.

What is the probability of a homozygous dominant offspring for these two parents?
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Composition of Genotypes

What is the probability of a homozygous dominant offspring for these two parents?
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Now let us talk about the composition of genotypes. A genotype like BB or bb has alleles identical. When a person has this type of genotype, he is known as homozygous. When a genotype is like Bb, the alleles will be different from each other. When an individual has this kind of pairing, this case will be heterogeneous.

Parents and Descendants

Each of the parents possesses a pair of alleles. The parents individually give one of these alleles to their progeny. This is how the descendant derives the pair of its alleles. When we know the parents' genotype, we can expect the genotype and phenotype of the descendant. It has been observed that 50% of each parent's alleles are carried forward to the descendant.

Now, let's again talk about the case of hair color. Both the parents have black hair, have genotype Bb and are heterozygous; there's a chance that each of the parents has a 50% chance of passing down the allele B (which is dominant). There's also a 50 % chance of passing down allele b (recessive).

Below is a gene and allele diagram for better understanding:

What is the probability of a homozygous dominant offspring for these two parents?
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Punnett squares

The enumeration above can be more concisely shown by employing a Punnett square. Representation like this is named after Reginald C. Punnett.

What is Punnett square?

A Punnett square comprises a tabular representation that registers all the possible genotypes of the descendant. The parents' genotypes are usually marked outside the Punnett square. The input of each cell in the table is decided by observing the alleles in the column and row of that input.

What is the probability of a homozygous dominant offspring for these two parents?
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Let’s put together Punnett square examples for all probable conditions of a single characteristic.

When both parents are homozygous:

All the descendants will possess a matching genotype when both mother and father are homozygous. Let's study the cross between BB and bb. In the tabular presentation below, the parents are represented in bold.

What is the probability of a homozygous dominant offspring for these two parents?

Now all the descendants are heterogeneous, with the genotype of Bb. What's a monohybrid cross Punnett square? This is a tabular representation of a genic combination between two persons who have homozygous genotypes (genotypes having recessive alleles or completely dominant alleles).

When one parent is homozygous:

When one parent is homozygous, the other parent is heterozygous. The Punnett square from one homozygous parent and one heterozygous parent is below.

What is the probability of a homozygous dominant offspring for these two parents?

When the parent is homozygous and has two dominant alleles, all the descendants will have the same dominant trait phenotype. To put it another way, there is a ten out of ten possibility that when a descendant has a pairing of that nature, this pairing will show the dominant phenotype. Now we can also study that there is a possibility that the homozygous parent has two recessive alleles. Now half of the descendants will show the recessive trait with genotype bb. The other half will show the dominant trait, with heterozygous genotype Bb.

What is the probability of a homozygous dominant offspring for these two parents?

When both parents are heterozygous:

When both the mother and the father are heterozygous, both parents will possess the same genotype consisting of one dominant allele and one recessive allele. Based on the above circumstances, the Punnett Square is represented below. Here we see three ways in which an offspring can exhibit a dominant trait, and there is one way for a recessive trait. This means a 25% chance that an offspring will have a recessive trait and a 75% chance that an offspring will have the dominant trait.

What is the probability of a homozygous dominant offspring for these two parents?

What is a dihybrid Punnett square?

In this case, both parents are heterozygous, and one allele for each characteristic shows absolute dominance. This means that both parents have recessive alleles but exhibit the dominant phenotype.

What is a trihybrid cross Punnett square?

A trihybrid cross is a type of Punnett square generated for 3 traits. This kind of Punnett square is a table of 64 boxes, created with the combinations of 6 mother's and 6 father's alleles.

Conclusion:

  • Punnett square is useful in calculating the probabilities of offspring with certain genetic characteristics.
  • The frame of a Genetic material known as Alleles determines the traits of an individual.
  • When a person has Identical Alleles, he is known as homozygous, and when the alleles are different, he is heterogeneous.

FAQs:

1. How do Punnett squares predict the probability?

A Punnett square predicts the percentages of phenotypes in the descendant by studying across from recognized genotypes of both parents.

2. How do you find the probability of offspring using a Punnett square?

Find out the total number of boxes in the particular Punnett Square. This will provide the total figure of offspring predicted. Now you divide the (number of occurrences of the phenotype) by (the total number of offspring). You have to multiply the number from step 4 by 100, and you will obtain your percent.

3. How do you find the probability of an offspring?

You have to divide the number of boxes having an allele dominant by four. Now you multiply the result by 100. This result gives you the probability that an offspring will have the dominant trait. For example (2/4)*100 = 50, therefore there is a 50% probability of an offspring having brown hair.

4. What is probability and how does it relate to genetics?

Probability is a technique applied to predict the possibilities of indefinite results. It is significant for the domain of genetics. It is applied to tell the traits concealed in the genome by the dominant alleles.

5. What is the probability of a heterozygous offspring?

There is a 50% x 50% = 25% probability that both of the alleles of the offspring are dominant. There is a 50% x 50% = 25% probability that both alleles of the offspring's are recessive. There is a 50% x 50% 50% x 50% = 25% 25% = 50% chance that the offspring is heterozygous.

6. How do you do a 4x4 Punnett square?

Making a 4x4 Punnett Square is quite challenging. However, it becomes easy when we use a dihybrid cross calculator.

We hope you enjoyed studying this lesson and learned something cool about Probability in Inheritance - Punnett Squares! Join our Discord community to get any questions you may have answered and to engage with other students just like you! Don't forget to download our App to experience our fun, VR classrooms - we promise, it makes studying much more fun! 😎

Continue your learning journey by learning more about genetics:

1. Mendelian Genetics 2. Non Mendelian Genetics 3. Population Genetics 4. Nucleic Acids

Sources:

  1. Punnett Squares. https://flexbooks.ck12.org/cbook/ck-12-biology-flexbook-2.0/section/3.6/primary/lesson/punnett-squares-bio/ Accessed 11 Dec, 2021.
  2. Probability and Punnett Squares in Genetics. https://www.thoughtco.com/probability-and-punnett-squares-genetics-4053752 Accessed 11 Dec, 2021.
  3. Difference Between Monohybrid And Dihybrid. https://www.vedantu.com/biology/difference-between-monohybrid-and-dihybrid Accessed 11 Dec, 2021.
  4. Dihybrid Cross Punnet Square Calculator. https://www.omnicalculator.com/biology/dihybrid-cross-punnett-square Accessed 11 Dec, 2021.

What is the probability of a homozygous offspring?

The Punnett square below makes it clear that at each birth, there will be a 25% chance of you having a normal homozygous (AA) child, a 50% chance of a healthy heterozygous (Aa) carrier child like you and your mate, and a 25% chance of a homozygous recessive (aa) child who probably will eventually die from this ...

What are the chances or probability of the couple having a homozygous tall offspring?

So, the correct option is '50%'.

What is the probability that two heterozygous parents?

What is the probability of a heterozygous offspring? There is a 50% x 50% = 25% probability that both of the alleles of the offspring are dominant. There is a 50% x 50% = 25% probability that both alleles of the offspring's are recessive.

What is the percentage of a homozygous dominant?

When F1 generation is selfed, 50 % of the progeny is homozygous i.e.25 per cent are homozygous recessive and 25 per cent of homozygous dominant individuals. Remaining 50% are heterozygotes. Thus the genotypic ratio is 1:2:1.